Well this is definitely a verse that we can all turn to and relate with. Who's with me? We all know the worn out feeling of exhaustion. Who hasn't said.... 'just give me five minutes'? Even God needed a day of rest on the seventh day after creating everything into existence.
We do get tired in more ways than just physically. We are warned not to grow tired in doing good. Sometimes we get tired of our efforts not being appreciated but we are told to do things as unto the Lord, not for man.
Our bodies are not sustainable forever and sometimes we are renewed in strength by the help of others. As in Exodus 17;12..........''When Moses’ hands grew tired, they took a stone and put it under him and he sat on it. Aaron and Hur held his hands up—one on one side, one on the other—so that his hands remained steady till sunset.'' We must not let pride stand in the way of how God uses others to help us. I know for myself, I preserve the energy God gives me for the things that are of benefit to me and Him most.
I asked my doctor once...'can you give me something for energy?' He recommended just a Flintstone vitamin but I'm going to add this verse to my daily regimen too.